He Shou Wu Extract

He Shou Wu Extract

He Shou Wu.png

MIGU supplied He Shou Wu Extract 10:1, 20:1, 30:1, 40:1, 50:1 and other standard purity and OEM service with analysis meets the EP, USP, JP, CP.....

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He Shou Wu Extract 10:1, 20:1, 30:1, 40:1  offered by 17 years experienced cGMP manufacturer with warehosues in China 

Latin Name: Polygonum Multiflorum Thunb
Material Original: Southwest,China
Extracted Part: Root
Supported Purity: tetrahydroxyl diphenylethylene-2-o-glucoside 10%~95%


What is the He Shou Wu 

He Shou Wu (pronounced huh – similar to English “huh”, but not as open – show woo) is one of the
most popular and highly revered tonic herbs in Asian herbalism. He Shou Wu is the prepared tuberous
root of Polygonum multiflorum, a plant that grows in the mountains of central and southern China. It
shares the position as the primary essence (Jing) tonic of Chinese herbalism with the Goji berry.

The Wild HeShouWu 

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Active Constituents of He Shou Wu 

The tuberous root of Polygonum multiflorum (He Shou Wu) has many active constituents. He Shou
Wu is rich in anthraquinones, including many phospholipids such as lecithin (3.7%). A stilbene glycoside
known as 2,3,5,4-tetrahydroxystilbene-2-O-β-D-glucopyranoside (henceforth refered to as “he shou 
wu super-glycoside”) is considered to be the principle active constituent responsible for He Shou Wu’s
very powerful antioxidant activity. There are many similar stilbene glycosides present in He Shou Wu.
The stilbene glycosides in He Shou Wu are very similar to resveratrol. Several of the stilbene
glycosides in He Shou Wu are stronger antioxidants than resveratrol.


By virtue of its ability to accumulate tremendous quantities of Qi into its root, this herb can tonify the
human and animal organs and can tonify and nourish the blood. He Shou Wu is not a stimulant.
However, it is one of the greatest energy tonics known to mankind. Its action is cumulative, as any
truly healthy tonic dietary supplement would be. Because it is a very mild sedative, it will calm the
nervous system. So it can be said that He Shou Wu is both energizing and calming. That is the magic
of a great tonic herb.


Our He Shou Wu Planted Base In GuiZhou,China 

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The Science of He Shou Wu

Difference betwwen“Prepared” and“not prepared”

The tuber of He Shou Wu (Polygonum multiflorum) must be “prepared” in order to be used as a
regularly-consumed tonic herb. Unprepared He Shou Wu does not possess the tonic effects and can have
unwanted side effects. The freshly picked tubers are sliced, stewed in black bean soup (in a proportion of
10 parts He Shou Wu to 1 part black beans) until the soup is exhausted. The “prepared” roots are then dried.
That is all there is to the “preparation.” Of course, no chemicals are used in the making of “prepared” He Shou Wu.

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“Prepared” versus “raw” He Shou Wu 

The tuber of He Shou Wu must be “prepared” in order to be used as a regularly-consumed tonic herb. The
roots are sliced, gently stewed in black bean soup (in a proportion of 10 parts He Shou Wu to 1 part black beans)
until the soup is exhausted. The “prepared” roots are then dried. That is all there is to the “preparation.” Of
course, no chemicals are used to prepare He Shou Wu.

Why Prepared He Shou Wu Extract Is Much Milder and Safer than Unprepared He Shou Wu Extract

The conjugated anthraquinones (such as emodin) present in unprepared He Shou Wu are laxative. After
preparation, the amount of conjugated anthraquinones in He Shou Wu decreases, while the free form 
anthraquinones that have many health-supporting and protective benefits significantly increase. This is
why prepared He Shou Wu has a much milder or nil laxative effect compared to raw, and why prepared He
Shou Wu is so safe and effective.  

Efficacy and Function Difference: The “preparation” eliminates the laxative effect of He Shou Wu and
brings out the tonic effect. In addition to toxicity elimination, the special preparation process also enhances
He Shou Wu’s therapeutic efficacy. He Shou Wu is known to support macrophages. In a test where mice
were fed He Shou Wu prepared by different methods, or not prepared at all, at the dose of 6g/kg, only the
prepared He Shou Wu that was stewed and steamed with black soybean soup for 32 hours was shown to
support the phagocytic activity of abdominal macrophage. He Shou Wu that was raw or prepared differently
showed no obvious results.

Raw, un-prepared He Shou Wu is used as a laxative in Chinese herbalism, and is not used in tonic herbalism.

Our HeShouWu 

Our He Shou Wu products are always made from PREPARED He Shou Wu. Unfortunately, many nutritional
supplement companies and marketers in America are unaware of this distinction between prepared and
un-prepared He Shou Wu (Polygonum multiflorum). Raw He Shou Wu is of course less expensive, and that
is often the driving force behind the way many herb companies make their purchasing decisions. As a result,
He Shou Wu is sometimes blamed for the unwanted side effect of loose stool that results from the use of the
incorrect herb (raw He Shou Wu). Again, Our is extremely aware of this issue and only uses PREPARED He
Shou Wu to make its tonic products.*

The Specification We Provided  for He Shou Wu Extract from MIGU

specification of He Shou Wu extract.jpg

Function and benefits of He Shou Wu Extract

Prepared He Shou Wu extract increases the cellular antioxidant activity 

He Shou Wu supports the body’s innate ability to efficiently clear superoxide, the highly reactive pro-oxidant
(free radical), from the body. This is a normal function that occurs trillions of times a day in every human being.

All organisms maintain complex innate antioxidant systems to prevent damage by oxidation. Antioxidants are
chemicals that reduce the rate of oxidation reactions. Oxidation reactions are chemical reactions that involve
the transfer of electrons from one substance to an oxidizing agent.

Oxidation is a constant function of life that is accelerated by stress and many other factors. He Shou Wu is rich
in potent antioxidants and in antioxidant-potentiating molecules.
Superoxide dismutase (SOD) 

Superoxide dismutase, generally referred to as SOD, is a class of closely related enzymes produced within
the human body. Of all the antioxidants produced in the human body, SOD is king. SOD proteins are present
in almost all aerobic cells and in almost all extracellular fluids. SOD transforms the superoxide radical into ions
that are less reactive. These less reactive ions are then further transformed by the antioxidants catalase and
glutathione into safe molecules. This transformation, called dismutation, is essential to life. He Shou Wu
supports the normal dismutation process.

SOD is much more powerful than any other antioxidant. No external antioxidant is comparable to SOD, as
external antioxidants may deteriorate by the time they enter our blood stream and because they cannot match
SOD’s performance in clearing free radicals.

He Shou Wu has been shown to help maintain youthful levels of SOD in laboratory animals even as they age.
It is widely believed that the SOD generating capacity of He Shou Wu is one of the reasons it has been found
to have anti-aging and longevity increasing activity.

He Shou Wu enhances immunity 

He Shou Wu has been found to support fundamental immunological functions in mammals.

He Shou Wu enhances adrenocortical function 

He Shou Wu has been found to support adrenal gland functioning. He Shou Wu supports adrenal fortitude. He
Shou Wu traditionally functions as a Kidney tonic. Jing controls the functions of adrenal cortex.

He Shou Wu’s Blood Tonic Actions 

He Shou Wu enhances the proliferation of blood producing cells

Scientific research supports He Shou Wu’s traditional function as a blood tonic. Prepared He Shou Wu can
supports the hematopoietic(blood producing) function of the body. It does this by directly promoting the blood
generating hematopoietic stem cells.

Improves red blood cell membranes

Extracts of this herb have been demonstrated to help support the membranes of erythrocytes (red blood cells)
and to support the growth and development of erythrocytes in test animals.

He Shou Wu is a rich source of lecithin which is an important raw material of red blood cell and other cell
membranes (lecithin is also a major component of nervous tissues).

Contains iron

He Shou Wu contains iron, even more than other blood tonics such as Dang Gui and Goji. 

Supports Circulation 

Prepared He Shou Wu supports blood flow and in test animals.

Protects the Liver

Classically, He Shou Wu is considered a Liver tonic. Many studies now support He Shou Wu’s protective and
function-regulating actions on the liver. Throughout our lifetime liver cells continually replenish themselves.
Adult humans do not die with the same liver they were born with. In experiments on mice, prepared He Shou
Wu helps maintain healthy structural integrity of the liver. He Shou Wu acts as a powerful antioxidant in the liver.

Furthermore, researchers have found that this herb can stabilize liver cells by supporting membrane mechanism.
He Shou Wu is a good source of plant lecithin. He Shou Wu has a special tropism (attraction) to the liver.

A zinc supplement

He Shou Wu Extract contains zinc. The zinc content of prepared He Shou Wu is as high as 42 mg per 100 grams the
herb. This is several dozen times higher than that of most herbs. Animal type foods are considered to be high
in zinc, but they only have 3-5 mg per 100 gram, much lower than the 42 mg in He Shou Wu.

Zinc is an essential trace mineral required by all forms of life. Numerous aspects of cellular metabolism are
zinc-dependent. Zinc plays important roles in growth and development, the immune response, neurological
function, and reproduction. On the cellular level, the function of zinc can be divided into three categories: (1)
regulatory, (2) catalytic, and (3) structural.  Zinc supports the metabolism of testosterone, and supports sperm
quality and motility.

Effect on Memory

Dietary supplementation with either ethanol or water extracts of He Shou Wu can help maintain brain function
and support learning and memory ability.

Potential Adverse Effects of He Shou Wu Extract

Adverse effects are not common (very rare) with extracts of properly prepared He Shou Wu. Potential adverse
effects of this herb are mainly digestive canal reactions, usually resulting in thin stool in cases where the herb
is not tolerated, and occasional light abdominal pain, nausea, and vomiting. Raw, unprepared He Shou Wu is
a laxative and should not be consumed as a tonic herb, i.e. on a long term basis. Some companies of He Shou
Wu products are unaware of this issue and sell unprepared He Shou Wu, resulting in adverse effects.


He Shou Wu is considered to be a very mild and safe herb. Mild gastrointestinal disturbance, characterized by
soft stool, is the only side effect associated with Polygonum multiflorum. However, moderate doses of processed
He Shou Wu rarely result in such an effect. Should this occur, the herb may be combined with certain other
herbs, and the problem can be eliminated. Consult your herbalist. Again, this side effect is rare.

More scientific information for He Shou Wu Extract please check here


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