Ganoderma Lucidum Extract Inhibit the generation of diabetic complication
For all of known, ganoderma lucidum polysaccharide can improve diabetes through adjust blood glucose, promote the secretion of insulin, protect the the insulin cells. Now, people found and get more functional of ganoderma to diabetes. The study from Kyushu university in Japan said ganoderic acid which extract frm ganoderma lucidum fruit body by the solvent of trichloromethane can restrain the activie of aldose reductase to prevent or delay diabetic complication.
The ganoderic acid is an kind of enzymes who lived in tissues such as nerve cells , lens , retina , red blood cells. The aldose reductase who usually be stationary state will be activated when the blood sugar too high and will converse of glucose to sorbitol in the body. When we meet much of sorbitol accumulate in the body, it will damage the metabolism and functionof the cells. Which is one of the leading causes of kidney, vascular lesions and eye illness by diabetes people.
Ganoderma Lucidum Extract Inhibit the generation of diabetic complication
The inhibition function of aldose reductase activity by ganoderic acid will be befefits to prevent of diabetic complications. It will improve the living security of diabetes people. Further analysis to the ganoderma lucidum extract ganoderic acid, we can found this ingredient mainly contents: ganoderic acid A, ganoderic acid C2, and other 3 similar ingredients to compose which is relationship to its chemical structure of hydroxyl groups ( -COOH).
In 2005,the similar reaserch reports from Korea also said the fruit body of Ganoderma applanatum extract which used solvent of methanol have the restrain function of aldose reductase. They also said the mainly ingredient is protocatechualdehyde.
Besides these, one report from University of South Korea xiking said Ganoderma methyl alcohol extract contents the active ingredients who can lower cholesterol levels. And other two reports which from Korea and Japen also show ganoderma lucidum extract and its triterpenes ingredients can promote or inhibit adipogenesis fat metabolism through regulation of some keygene or protein (PPARγ ， PPARα, SREBP-1c) . All of these functions can help and improve the people who are diabetes and metabolic syndrome.More Scientific research and development , please check here
